panasonic med64 system  (Panasonic Healthcare)

Journal: Frontiers in Neuroinformatics

Article Title: ToolConnect: A Functional Connectivity Toolbox for In vitro Networks

doi: 10.3389/fninf.2016.00013

Figure Lengend Snippet: toolconnect 's GUI . The main Graphic user interface is running under Windows; in the bottom left (blue box), it is possible to see the graphic Selection of the Electrodes to analyze (Electrodes format MEA 60 Multichannel System). The red box shows the components of the graphical section; the black box indicates the one relative to the computational section. In this example, the program was used to work with a CM (plot the CM, the TCM and the connectivity graph) and to perform a cross and partial correlation analysis.

Article Snippet: In the current version of the software, the subset of electrodes selection has been conceived for the main commercial acquisition systems, that are the 60, 120, and 252 MCS MEAs, the 64 electrodes Panasonic MED64 (Osaka, Japan), the 4096 electrodes 3Brain APS system.

Techniques: Selection

Journal: Frontiers in Neuroinformatics

Article Title: ToolConnect: A Functional Connectivity Toolbox for In vitro Networks

doi: 10.3389/fninf.2016.00013

Figure Lengend Snippet: Example of toolconnect 's graphical output. (A) Three neurons simulated neural network (B) , Cross-correlograms computed among the three electrodes. (D) Partial correlograms computed among the three electrodes. (C,E) Correspondent TE and the JE matrices. The peak appearing for the cross- and partial correlograms 12 vs.13 and 12 vs. 21 corresponds to a connection found between the aforementioned electrodes. In the same way, the TE presents the highest values for the couples (12, 13) and (12, 21) and the joint entropy shows the smallest values for the same couples; meaning that these methods found a connection between the aforementioned electrodes. Regarding the electrodes 13 and 21, instead, the absence of peak in the cross-and partial correlograms, the low values for TE and the high values for JE suggest the absence of a connection, as the sketch of the panel (A) shows.

Article Snippet: In the current version of the software, the subset of electrodes selection has been conceived for the main commercial acquisition systems, that are the 60, 120, and 252 MCS MEAs, the 64 electrodes Panasonic MED64 (Osaka, Japan), the 4096 electrodes 3Brain APS system.

Techniques:

Journal: Frontiers in Neuroinformatics

Article Title: ToolConnect: A Functional Connectivity Toolbox for In vitro Networks

doi: 10.3389/fninf.2016.00013

Figure Lengend Snippet: Example of toolconnect 's CM and connectivity graph. (A,B) Examples of CM and TCM (obtained with n = 1) for a simulated network with medium average degree of connections (60 neurons, 30 mean connections per neuron). (C–E) Connectivity graph for the acquisition system MEA 60, 120, and 252 from Multi Channel Systems (MCS) respectively. (F) Example of unknown format (49 electrodes extracted from the aforementioned simulated neural network).

Article Snippet: In the current version of the software, the subset of electrodes selection has been conceived for the main commercial acquisition systems, that are the 60, 120, and 252 MCS MEAs, the 64 electrodes Panasonic MED64 (Osaka, Japan), the 4096 electrodes 3Brain APS system.

Techniques:

Journal: Frontiers in Neuroinformatics

Article Title: ToolConnect: A Functional Connectivity Toolbox for In vitro Networks

doi: 10.3389/fninf.2016.00013

Figure Lengend Snippet: toolconnect 's application to mature hippocampal assemblies . TOOLCONNECT's application to mature hippocampal assemblies. Cross-correlation algorithm was applied to hippocampal networks in spontaneous and stimulus-evoked conditions. (A,D,G) connectivity graph, connectivity matrix and degree distribution for spontaneous activity. (B,E,H) connectivity graph, connectivity matrix and degree distribution for stimulated activity (site of stimulation, electrode 45). (C,F,I) Connectivity graph, connectivity matrix and degree distribution for stimulated activity (site of stimulation, electrode 21).

Article Snippet: In the current version of the software, the subset of electrodes selection has been conceived for the main commercial acquisition systems, that are the 60, 120, and 252 MCS MEAs, the 64 electrodes Panasonic MED64 (Osaka, Japan), the 4096 electrodes 3Brain APS system.

Techniques: Activity Assay

Journal: Frontiers in Neuroinformatics

Article Title: ToolConnect: A Functional Connectivity Toolbox for In vitro Networks

doi: 10.3389/fninf.2016.00013

Figure Lengend Snippet: Graph Theory's analysis of hippocampal neural assemblies. (A) Cluster coefficient. (B) Path length. (C,D) Number of links and number of neurons found after the thresholding procedure, respectively. (E) PSTH relative to the stimulation of electrode 45. (F) PSTH relative to the stimulation of electrode 21.

Article Snippet: In the current version of the software, the subset of electrodes selection has been conceived for the main commercial acquisition systems, that are the 60, 120, and 252 MCS MEAs, the 64 electrodes Panasonic MED64 (Osaka, Japan), the 4096 electrodes 3Brain APS system.

Techniques: